Mannose binding protein - innate protective immunity against pathogens by discrimination of self-nonself
Model according the X-ray structure of cluster of 3 C-type CRDs and neck region of coiled-coil helices.
Binding sites are adjusted for recognition of extended bacterial and fungal sugar arrays, yet do not permit multivalent binding of mammalian endogenous high-mannose oligosaccharides.
From Weis, WI and Drickamer, K (1994) Structure 2, 1227-1240